ABSTRACT
Novel safe and stable teracationic Zinc phthalocyanine is efficient against bacteria, fungi and viruses also under indoor light Recently a novel photosensitizer with outstanding properties, phthalocyanine LASU has being developed. The compound possesses unprecedented stability and antimicrobial activity. It can be activated by a weak indoor light of 270 lux and shows the activity against G+ and G- bacteria as well as fungi and viruses. Over 3 log inactivation of bacteria and fungi on the surface of a LASU-impregnated material can be achieved in 1/2-1 h of illumination with a regular indoor and/or natural light. A cotton filter impregnated with 0.1 g/m2 of LASU eradicates on its surface the coronavirus HCoV-229E by 3.5 log in 30 minutes under indoor/natural light of 500 lux. The molecule is photostable and remains active for weeks with no significant bleaching. Another remarkable property is its ability to bind to cellulose support. It readily attaches to a fiber substrate through electrostatic interactions, moreover, the size of LASU ring matches the pitch of cellulose polymer, making the conjugate unusually strong. Hence the compound does not leech to water and is stable against temperature and surfactants. The toxicology studies also reveals that substance is non-irritating for human skin, and is non-mutagenic, which makes it suitable for human-wearable items.Copyright © 2023